“Dr. Childs and her staff told me beforehand about the good and the bad of chemotherapy and let me know what to expect. I ended up losing all of my hair for a period. They said this would happen, but it was still traumatic. But when that happened, or when other side effects that they had told me about happened, they were always there, being supportive and offering practical suggestions. It wasn’t just Dr. Childs; it was all of the nurses and other people who work with her. I want to name all of them, but I am afraid I’ll forget someone.”
Ms. Pantellas continues, “Beyond being very nurturing to me, they were very kind to my husband, who accompanied me to every doctor’s appointment and every chemo session. “If anybody ever said to me, ‘What kind of care did you receive at this office?,’ the only thing I can say is that five stars is not enough because it was just unbelievable care, and because of that care, I’m doing OK now.”
After several chemotherapy sessions, Ms. Pantellas was able to switch to an oral medication, known as a poly (ADP-ribose) polymerase – or PARP – inhibitor. PARP is a protein that enables cancer cells to survive and grow by repairing functional problems with their DNA. PARP inhibitors prevent the protein from accomplishing those DNA repairs, causing the cancer cells to die. Ovarian cancer patients who have a BRCA gene mutation or another genetic condition called homologous recombination deficiency may be candidates for the PARP inhibitor that Ms. Pantellas is taking, although the Food and Drug Administration (FDA) specifies that such patients should receive the medication only after responding to chemotherapy.
“So now I’m in remission, and they’re even reducing the dose of the medication I take. I wouldn’t say that I’m 100%, but I’m much better. I had lost a tremendous amount of weight, and I’m not a big person to begin with, but I’ve gained back much of the weight now,” Ms. Pantellas says, continuing, “In those moments when you’re by yourself, you’re thinking, ‘Am I really going to be OK?’ but then I think of the support I have received, of the great care I have received, and it gives me cause to be encouraged.” She adds, “Dr. Childs is the only doctor who has ever given me her phone number and said, ‘If you’re not feeling well over the weekend or have questions, call me.’ And she calls you back, not someone on her staff!”
New Cancer and Compassionate Support Offer Hope
Julianne W. Childs, DO, Ms. Pantellas’ medical oncologist, says, “People facing cancer deserve excellent medical care, but they also need – and deserve – support and a sense of hope that reflects both the reality of their particular medical situation and the incredible advances in treatment that have transformed cancer care in the last decade or so. PARP inhibitors and other targeted therapies that act against specific genetic mutations or cancer processes, immunotherapies, enhanced chemotherapy regimens, protocols for managing chemotherapy side effects, and other innovations enable us to offer patients so much more – in terms of both care and hope – than we could when I began practicing medicine. I am delighted that we can provide patients like Ms. Pantellas effective treatments, expanded options, and greater reason for optimism. I just hope that she and our other patients realize how much they inspire us with their strength and courage.”
Knowing Yourself, and Advocating for Yourself
While praising Dr. Childs and the other healthcare professionals treating her, Ms. Pantellas stresses that people bear the first – and ultimate – responsibility for their own health. “You have to know your own body, and you have to be proactive. If you’re experiencing something unusual, don’t just say, ‘It will go away.’ There are things that won’t go away and that, if untreated, can become very serious problems. I don’t think I would be standing here right now if I did not go to the doctor when I did. I have a wonderful family and I’ve been totally blessed, and I am so grateful for the care I have received, but I am also grateful that I recognized that something was off and that I gave myself a chance to keep living.”
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Dr. Childs is a board-certified medical oncologist and hematologist who has practiced at Hope Community Cancer Center in Cape May Court House and Marmora, NJ, for more than 20 years. After receiving her medical degree from the University of Health Sciences in Kansas City, MO, Dr. Childs completed her internal medicine residency and hematology/oncology fellowship at the University of Medicine and Dentistry of New Jersey. Along with her Hope Community Cancer Center colleagues Kaleem Ahmad, MD; Hemang Dave, MD; and Fatima Fayyaz, MD; Dr. Childs is among 100+ medical oncologists and hematologists who practice with Regional Cancer Care Associates (RCCA), one of the nation’s largest networks of oncology specialists. RCCA has more than 20 locations near you across New Jersey, Connecticut, Massachusetts, and the Washington, D.C., area. RCCA’s cancer specialists see more than 30,000 new patients each year and provide care to more than 265,000 established patients, collaborating closely with those patients’ other physicians. RCCA physicians offer patients innovative therapies, including immunotherapies and targeted therapy, as well as access to approximately 300 clinical trials. In addition to serving patients who have solid tumors, blood-based cancers, and benign blood disorders, RCCA care centers also provide infusion services to people with a number of non-oncologic conditions—including multiple sclerosis, Crohn’s disease, asthma, iron-deficiency anemia, and rheumatoid arthritis—who take intravenously-administered medications.
To learn more about RCCA, call 844-346-7222 or contact RCCA.
Know the Early Signs of Ovarian Cancer
The American Cancer Society estimates that 20,890 women across the United States will be diagnosed with ovarian cancer this year.1
Unfortunately, only about 20% of new cases are detected at an early stage,2 when the cancer can be treated most effectively. Experts say that two factors make early diagnosis challenging. First, there is not a highly effective means to screen for ovarian cancer in the way that, for example, colonoscopy can help identify colorectal cancer. Physicians can perform transvaginal ultrasound to evaluate the ovaries when there is a concern, but the imaging cannot determine if an unusual mass is cancerous. Most suspicious masses found on ultrasound prove to be benign when a follow-up biopsy is performed.2 Similarly, oncologists can track changes in blood levels of a protein called CA-125 to monitor how women already diagnosed with ovarian cancer are responding to treatment, but the blood test has not proven useful as a screening measure to identify possible ovarian cancer.2
The second obstacle to early diagnosis is that the symptoms of ovarian cancer are conditions that many women experience from time to time and that most often are due to other, less-serious causes. The most common symptoms of ovarian cancer include:
- Bloating
- Pelvic or abdominal (belly) pain
- Trouble eating or feeling full quickly
- Urinary symptoms such as urgency (always feeling like you have to go) or frequency (having to go often)3
Other, less-common symptoms include:
- Fatigue
- Upset stomach
- Back pain
- Pain during sex
- Constipation
- Menstrual changes, such as heavier bleeding than normal or irregular bleeding
- Abdominal (belly) swelling with weight loss3
While having one or more of those symptoms is not cause for panic, it is a reason to see your primary care physician, gynecologist, or other healthcare provider for evaluation. Prompt attention to one or more of those symptoms is particularly important if you have not experienced them previously, if they are severe, or if they are increasing in frequency or severity.
In addition to seeing your doctor when concerning symptoms occur, having regular check-ups with your primary care provider or gynecologist also is essential for maintaining overall health and enabling early identification and assessment of potential signs of cancer or other serious conditions.
References:
- American Cancer Society. Cancer Facts & Figures 2025.
- American Cancer Society. Can ovarian cancer be found early? Available at https://www.cancer.org/cancer/types/ovarian-cancer/detection-diagnosis-staging/detection.html. Accessed April 8, 2025.
- American Cancer Society. Signs and symptoms of ovarian cancer. Available at https://www.cancer.org/cancer/types/ovarian-cancer/detection-diagnosis-staging/signs-and-symptoms.html. Accessed April 8, 2025.