Common Breast Cancer Risk Factors
Anybody can develop breast cancer. However, certain factors can increase a person’s likelihood of breast cancer. Some of these factors can be controlled or reduced through individual choices, while others cannot. Common breast cancer risk factors include:
Age
The risk of breast cancer steadily increases as people age. Most patients with breast cancer are diagnosed after age 40. The median age of diagnosis is 62 years old for women and 67 for men, with people age 70 and older facing the highest risk. Certain developmental milestones may also affect a person’s risk. If a woman started menstruation before age 12 or started menopause after age 55, she may be more likely to develop breast cancer.
Sex
More women get breast cancer than men. It is important to remember, however, that men may also develop breast cancer. When men do, it is often detected in later stages than in women. This is largely due to lower awareness in men, who are not encouraged to receive routine screenings or taught how to conduct self-examinations.
Genetics
Certain inherited genetic mutations, such as BRCA1 and BRCA2 genes, are known risk factors for breast and ovarian cancer. Other, less common mutations that may increase cancer risks include ATM, TP53, PTEN, and STK11. RCCA offers genetic testing and counseling to help individuals understand when there might be at risk of developing breast cancer.
Medical History
If a person has been diagnosed with breast cancer at least once before, there is a higher risk of the cancer recurring either in the same or the other breast. Similarly, a person’s risk increases if a first-degree relative has been previously diagnosed with breast cancer. First-degree relatives include children, parents, and siblings.
Dense Breasts
Dense breasts contain more connective tissue and less fat. Because most breast cancer starts in connective tissue, a higher percentage corresponds to a higher risk. It may also be more difficult to detect cancer in dense breasts, as mammogram imaging shows tumors less clearly. New technologies, however, are making it easier to examine dense breast tissue. Specialists frequently use 3D mammography and ultrasounds to improve breast cancer detection.
Reproductive History
Women who become pregnant at an early age or who become pregnant after age 30 face a higher risk of developing breast cancer. Women who have never carried a pregnancy to full term are also at higher risk of breast cancer, as are women who never breastfed.
Diethylstilbestrol (DES)
Diethylstilbestrol (DES) was frequently prescribed for pregnant women from 1940 to 1971 to prevent miscarriage. Women who have used DES have a higher risk of developing breast cancer. If a woman’s mother used DES while pregnant with her, she may also have a higher risk of breast cancer.
Hormonal Medications
Some hormonal treatments may also cause a higher cancer risk. These include hormonal contraceptive methods, as well as the use of progestin or estrogen in post-menopausal hormone therapy, especially for more than five years. Research is ongoing regarding how hormonal medications impact cancer risk.
Radiation Therapy
Women who have received radiation therapy as a treatment for Hodgkin lymphoma or another cancer type face a higher chance of developing breast cancer later in life. This is especially true if the treatment was directed to the breasts or chest, or if it was received before age 30.
Chemical Exposure
Similarly to radiation, exposure to certain chemicals has been linked to higher breast cancer risks. Some of these chemicals are found in cigarettes. Quitting smoking is an important measure people can take to reduce their risk of cancer. Other cancer-causing chemicals are common in industrial environments that people may be exposed to at their workplace.
Weight and Diet
There are a variety of lifestyle choices people can make to reduce their risk of breast cancer. Maintaining a healthy weight, especially after menopause, can make cancer less likely. So can eating a healthy diet with fewer than two alcoholic beverages per day. Staying physically active has also been linked to lower cancer occurrence.
What to Do if You Are At Risk for Breast Cancer
If one or more of the above risk factors applies to a person, he or she should remember that these merely increase the likelihood of developing breast cancer. None of them is a guarantee. However, at-risk individuals should be proactive about their health. RCCA recommends the following steps to reduce the risk of cancer and improve the chances of early detection:
- Lifestyle changes: Individuals can mitigate certain factors by making healthier lifestyle choices, such as quitting smoking, reducing alcohol consumption, or losing weight.
- Routine screenings: If a person is at risk, he or she should talk to a healthcare provider about more frequent mammograms. This may improve the chances of detecting cancer early.
- Genetic testing: Individuals concerned about their cancer risk, especially due to family history, may consider genetic testing to confirm whether inherited mutations may be at play.
- Self-examination: People can learn how to check their breasts for lumps, discharge, changes in appearance, or other abnormalities that may indicate cancer.
- Learning more: Awareness is the first line of defense against cancer. Those who are concerned about cancer risk can educate themselves to make more informed choices about care.