Cancers Most Likely To Benefit From Targeted Monoclonal Immunotherapy
One of the most effective ways to treat cancer is to harness the power of the body’s own immune system. This method is called immunotherapy.
It is estimated that one in every eight men will be diagnosed with prostate cancer at some point in their lives. Cancer of the prostate continues to be a concern to all people assigned male sex at birth, especially older people.
Once doctors have determined that a patient has prostate cancer, their focus shifts to determining the cancer’s nature and status, including whether it has spread. This process is called staging. Knowing the stage of a patient’s prostate cancer enables medical oncologists to initiate the most appropriate care plan and to provide important information to patients and their families.
With a team of board-certified oncologists and hematologists, Regional Cancer Care Associates (RCCA) specializes in treating many types of cancer, including prostate cancer. With locations in New Jersey, Connecticut, Maryland, and the Washington, D.C., area, RCCA provides patients with personalized care plans and educates them on their conditions. Discover more about the different stages of prostate cancer and how each stage affects a patient’s treatment plan.
Prostate cancer develops when abnormal cells form and begin growing rapidly in the prostate gland. Located below the bladder and in front of the rectum, the prostate is a walnut-sized gland that is part of the male reproductive system. The main function of the prostate is to produce seminal fluid, which nourishes and transports sperm.
After thoroughly assessing a patient’s prostate cancer, medical oncologists will assign the cancer a stage. The staging system is standard for all cancer types and is used to characterize how far cancer has spread. The most widely used staging system for prostate cancer is the American Joint Committee on Cancer (AJCC) TNM system. Using this system, oncologists consider the following:
The main stages of prostate cancer range from I to IV. With this staging system, the higher the number, the more the cancer has spread.
Prostate cancer in its earliest stage is classified as Stage I. At this point, the tumor is only in the prostate gland and is very small and slow-growing. Patients with Stage I prostate cancer often do not notice any symptoms or health problems.
Additionally, the tumor may be difficult to detect during Stage I prostate cancer. A doctor may not be able to feel the tumor during a digital rectal exam or see it on an ultrasound scan. Detecting prostate cancer at this stage gives patients the greatest chance of cure and survival.
Treatment options for Stage I prostate cancer can include active surveillance, radiation therapy, and radical prostatectomy.
If undetected, early prostate cancer can progress to Stage II. Tumors in this stage are much larger than tumors in Stage I. Because of this, physicians are much more likely to recommend a more proactive treatment plan.
With Stage II prostate cancer, there is a greater chance of cancer coming back after treatment (recurrence). To guard against recurrence, continued surveillance and regular checkups are necessary.
Treatment approaches for Stage II prostate cancer generally are more aggressive than those used in Stage I. They can include active surveillance, radiation therapy, radical prostatectomy, and clinical trials, among others.
In Stage III prostate cancer, the cancer has started to spread and is no longer affecting only the prostate gland. At this point, the cancer also may be in nearby tissues, lymph nodes, or even distant organs. To help patients and their doctors gain control over the cancer, more aggressive treatment is typically required. In Stage III, the risk of recurrence also increases.
When treating Stage III prostate cancer, care plans can include several treatment options, including radiation therapy plus hormone therapy, radical prostatectomy, and clinical trials.
Stage IV prostate cancer is the most progressed form of the disease. When a patient is diagnosed with Stage IV prostate cancer, it means the cancer has already spread to nearby areas, particularly the bladder or rectum. It also may have spread to the lymph nodes, bones, lungs, liver, and other distant organs.
Due to the advanced nature of the cancer and how much it has spread, the 5-year survival rate decreases drastically. At this point, the goal of treatment is to control the cancer, extend survival, and make the patient as comfortable as possible.
Treatment options for Stage IV prostate cancer can include active surveillance, hormone therapy, chemotherapy, radiation, radical prostatectomy, surgery to relieve symptoms, and clinical trials.
Treatment options for patients with prostate cancer include:
In some cases, physicians and patients will opt for careful, regular monitoring of the cancer rather than a medical or surgical intervention. This approach, known as active surveillance, often is recommended if the cancer is small, is not causing any symptoms, is still only in the prostate, and is expected to grow slowly. Active surveillance usually involves doctor visits every six months, where healthcare professionals will perform various exams to remain up-to-date on the condition of cancer.
Radical prostatectomy is the surgical approach used most often in the treatment of prostate cancer. This operation entails the surgeon removing the entire prostate gland, plus some of the tissue around it, including the seminal vesicles. Surgery is a common option for treating prostate cancer if the disease is believed not to have spread outside the prostate gland.
Radiation therapy uses high-energy rays or radiation-emitting pellets or drugs to destroy cancer cells or slow their growth. There are several types of radiation therapies, such as:
Prostate cancer is fueled, at least in its early stages, by androgens, the male sex hormones. The goal of hormone therapy is to reduce a patient’s hormone levels to stop them from driving prostate cancer cell growth.
Hormone therapy for prostate cancer works in two ways. It either suppresses the body’s ability to make the hormones that fuel development of cancer or it interferes with the activity of those hormones. In many cases, hormone therapy is used in conjunction with other treatments.
Chemotherapy is one of the most common approaches to treating all types of cancers, including advanced prostate cancer. With this treatment, anti-cancer drugs are injected into a vein or given by mouth. Traveling through the bloodstream, these drugs are designed to reach cancer cells and attack and kill them.
Immunotherapy involves the use of medicines to stimulate a person’s own immune system to recognize and more effectively destroy cancer cells. Because the immune system is made up of many different parts, there are several different types of immunotherapy treatments, such as:
Targeted therapies act against specific cellular mutations that play a role in a cancer’s development and spread while not affecting healthy tissues.
The stage of cancer indicates how far along the disease is and how much it has spread. Knowing the stage of a patient’s prostate cancer is vital because it determines the appropriate course of action for treatment.
The board-certified medical oncologists and hematologists of Regional Cancer Care Associates specialize in treating blood disorders and a wide range of cancer, including prostate cancer. Serving individuals in New Jersey, Connecticut, Maryland, and the Washington, D.C., area, the RCCA medical team ensures that all patients receive the best possible care. Contact Regional Cancer Care Associates today for more information regarding prostate cancer treatment options or schedule an appointment at one of RCCA’s 20+ locations for treatment.
If you’ve been diagnosed with prostate cancer or are concerned about potential symptoms, contact RCCA today. Our team of cancer care specialists will assess the stage of your cancer using the latest diagnostic methods and work with you to design a fully individualized care plan that includes advanced treatment options, the potential for clinical trials, and support that addresses physical and emotional well-being. To speak with a representative right away, please call 844-346-7222.
One of the most effective ways to treat cancer is to harness the power of the body’s own immune system. This method is called immunotherapy.
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If you’ve been diagnosed with prostate cancer, the doctors at Regional Cancer Care Associates will take charge of your treatment plan, which usually involves medications,
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