Physicians use a staging system to describe the extent of a patient’s cancer. Stages are based on a combination of factors including the size of the tumor and how much it has spread. This information guides medical oncologists in determining the most appropriate treatment. It is important to note that many women and men who experience one or more of the symptoms will not have breast cancer. Nonetheless, it is important to consult a physician about these symptoms. Prompt evaluation will enable a doctor to address your concerns and to provide a treatment plan for whatever condition may be responsible for the symptoms.
There are five breast cancer stages:
Stage 0
Stage 0 breast cancer is also called ductal carcinoma in situ, or DCIS. During this stage, cancer cells are present in the milk ducts and are pre-invasive or non-invasive. This means they have not spread to nearby tissue. DCIS is usually treated with a lumpectomy and radiation therapy, and it rarely recurs.
Stage I
In Stage I breast cancer, tumor cells have spread to tissue outside the milk ducts. The tumor remains small and is limited to a small area. There are two substages:
- Stage IA: The tumor measures 2 centimeters or less and the cancer has not spread to the lymph nodes.
- Stage IB: A small number of cancer cells are found in lymph nodes close to the breast. There may be no tumor in the breast or a tumor that measures 2 centimeters or less.
Stage I breast cancer is typically treated with surgery, sometimes followed by radiation or hormone therapy. The five-year survival rate is 98% to 100%.
Stage II
In Stage II breast cancer, the tumor in the breast is larger and may have spread further into the lymph nodes. There are two substages:
- Stage IIA: The tumor measures between 2 and 5 centimeters, and the cancer has not spread to the lymph nodes. Alternatively, the tumor measures 2 centimeters or less and cancer cells are found in lymph nodes under the arm.
- Stage IIB: The tumor measures over 5 centimeters and has either not spread to lymph nodes or has spread only to a few. Or the tumor measures between 2 and 5 centimeters, and cancer cells are found in multiple lymph nodes.
Stage II breast cancer is typically treated using more than one therapy type, which may include surgery, radiation therapy, and chemotherapy. Multiple treatments help to eliminate as many cancer cells as possible for a lower chance of recurrence. Five-year survival rates are still very good at 90% to 99%.
Stage III
In Stage III breast cancer, the cancer has spread further into the breast or lymph nodes. There are three substages:
- Stage IIIA: The tumor measures between 2 and 5 centimeters, and cancer cells are found in four to nine nearby lymph nodes. Or the tumor measures over 5 centimeters and cancer cells are found in one to three nearby lymph nodes.
- Stage IIIB: The tumor, which may be any size, has spread into the chest wall or skin. Cancer cells may be found in up to nine underarm or internal mammary lymph nodes.
- Stage IIIC: The tumor may be any size. The cancer has spread to one or more of the following locations:
- 10 or more underarm lymph nodes
- Both underarm and internal mammary lymph nodes
- Lymph nodes above or below the collarbone
- The skin
As with Stage II, treatment for Stage III cancer is typically multimodal. Many patients begin with chemotherapy before having radiation therapy or mastectomy surgery to remove the breast tumor and cancerous lymph nodes. Survival rates are 87%.
Stage IV (Metastatic)
Stage IV is the most advanced stage of breast cancer. In this stage, cancer has spread or metastasized to other parts of the body beyond the breast. Parts of the body commonly affected include the bones, liver, lungs, and brain.
There is no known cure for metastatic breast cancer. Instead, treatment focuses on monitoring, slowing tumor growth, relieving symptoms, prolonging life, and improving quality of life. Recent scientific advances have led to expanded treatment options and greatly improved survival rates for patients with Stage IV metastatic breast cancer.