Breast Cancer Clinical Trials
Phase III
Enrolling
nct/study# NCT07060807 / MK1022-016
An Open-label, Randomized, Phase 3 Study to Evaluate Patritumab Deruxtecan Monotherapy versus Treatment of Physician’s Choice in Hormone Receptor positive, HER2-negative Unresectable Locally Advanced or Metastatic Breast Cancer (HERTHENA-Breast04)
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Breast Cancer Clinical Trials
Phase III
Enrolling
nct/study# NCT06841354 / MK2870-011
A Phase 3, Randomized, Open-label Study Comparing Efficacy and Safety of Sacituzumab Tirumotecan (sac-TMT, MK-2870) as a Monotherapy and in Combination with Pembrolizumab (MK-3475) Versus Treatment of Physician’s Choice in Participants With Previously Untreated Locally Recurrent Unresectable or Metastatic Triple-Negative Breast Cancer Expressing PD-L1 at CPS Less than 10 (TroFuse 11)
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Gastrointestinal (GI) Oncology
N/A
Enrolling
nct/study# N/A / CELL-FREE-DNA-MOLECULAR-PROF
Integrating Cell-Free DNA Molecular Profiles with Clinical Metadata to Inform Early-Stage Colorectal and Breast Cancer Outcomes
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Gastrointestinal (GI) Oncology
Phase II
Enrolling
nct/study# NCT06015724 / DARANIVOVAX-IST
A Phase 2 Study Evaluating the Efficacy of Anti-CD38 antibody in Combination with KRAS vaccine and Anti-PD-1 Antibody in Subjects with Pancreatic Ductal Adenocarcinoma and Refractory Non-Small Cell Lung Cancer
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Gastrointestinal (GI) Oncology
N/A
Enrolling
nct/study# N/A / HVSNONH-GEDJC
Clinical, Molecular and Prognostic Differences between Hispanic (H) and non-Hispanic (non-H) patients with gastroesophageal (GEJ)/gastric cancers (GC): Molecular classification by Multiplex Immunohistochemistry (mIHC) and Next-generation sequencing (NGS)
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Gastrointestinal (GI) Oncology
Phase III
Enrolling
nct/study# NCT06997497 / MK1084-012
A Phase 3, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy of MK-1084, Cetuximab, and mFOLFOX6 versus mFOLFOX6 With or Without Bevacizumab as First-line Treatment of Participants With KRAS G12C-mutant, Locally Advanced Unresectable or Metastatic Colorectal Cancer (KANDLELIT-012)
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