Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910

Non-Randomized Open-Label Phase 11 Study to Assess Oliparib Tablets as a Treatment for Subjects with Different HRD Tumor Status and with Platinum-Sensitive, Relapsed, High-Grade or High-Grade Endometriod Ovarian, Fallopian Tube, or Primary Peritoneal Cancer that Have Received at Least 1 Ptior Line of Chemotherapy

Type of Cancer
Ovarian Cancer

Sponsor
AstraZeneca

Protocol Number
D108161003

To Learn More Call
201-510-0910

A Phase 1/2, Open-Label, Safety, Pharmacokinetic and Preliminary Efficacy Study of Oral CO-1686 in Patients with Previously Treated Mutant EGFR Non-Small Cell Lung Cancer (NSCLC)

Type of Cancer
Lung

Site
East Brunswick

Sponsor
Clovis

Protocol Number
CO-1686-008 (Tiger X)

Cancer Diagnosis
Non-small cell lung cancer

Phase of Trial
1/2

Study Short Name
Tiger X

To Learn More Call
201-510-0910

A Phase III, Open-Label, Randomized Study Of MPDL3280A (Anti-PD-L1 Antibody) In Combination with Carboplatin+Paclitaxel With Or Without Bevacizumab Compared with Carboplatin+Paclitaxel+Bevacizumab In Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non-Small Cell Lung Cancer

Type of Cancer
Lung

Site
East Brunswick, Freehold, Somerville, Sparta

Sponsor
Genentech

Protocol Number
GO29436

Staging
4

Phase of Trial
3

Protocol Title
A Phase 3, Open-Label, Randomized Study Of Mpdl3280a (Anti-Pd-L1 Antibody) In Combination With Carboplatin + Paclitaxel With Or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab In Chemotherapy Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer.

To Learn More Call
201-510-0910

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Idelalisib in Combination with Obinutuzumab Compared to Chlorambucil in Combination with Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia

Type of Cancer
Leukemia

Site
East Brunswick

Sponsor
Gilead

Protocol Number
GS-312-0118

To Learn More Call
201-510-0910

A Phase 2 Study of the Efficacy and Safety Of ACP-196 in Subjects with Relapsed/ Refractory CLL and Intolerant of Ibrutinib Therapy

Type of Cancer
Leukemia

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
Acerta

Protocol Number
ACE-CL-208

To Learn More Call
201-510-0910

Phase 3, open-label trial of lenalidomide and low-dose dexamethasone with or without pembrolizumab (MK-3475) in newly diagnosed, treatment-naïve multiple myeloma who are ineligible for autologous stem cell transplant

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver, Mount Holly, Sparta

Sponsor
Merck

Protocol Number
3475-185

To Learn More Call
201-510-0910

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Patients With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation

Type of Cancer
Multiple Myeloma

Site
East Brunswick, Freehold, Howell, Little Silver

Sponsor
MILLENIUM

Protocol Number
C16021

To Learn More Call
201-510-0910

An open-label, multicenter, Phase IIIb study to assess the safety and efficacy of ribociclib (LEE011) in combination with letrozole for the treatment of men and pre/postmenopausal women with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior hormonal therapy for advanced disease

Sponsor
Novartis

Protocol Number
CLEE11A2404 CompLEEment-1

To Learn More Call
201-510-0910

Phase II, Open-Label, 2-Cohort Study of INCB050465, a PI3Kδ Inhibitor, in Subjects with Relapsed or Refractory Marginal Zone Lymphoma with or without Prior Exposure to a BTK Inhibitor

Type of Cancer
Hematological Malignancies

Sponsor
Incyte

Protocol Number
INCB 50465-204

To Learn More Call
201-510-0910<