[[{"@type":["BlogPosting"],"@id":"https:\/\/www.regionalcancercare.org\/news\/inherited-gene-changes-and-mutations-the-genetic-factors-of-lung-cancer\/#BlogPosting","@context":{"@vocab":"http:\/\/schema.org\/","kg":"http:\/\/g.co\/kg"},"url":["https:\/\/www.regionalcancercare.org\/news\/inherited-gene-changes-and-mutations-the-genetic-factors-of-lung-cancer\/","https:\/\/www.regionalcancercare.org\/news\/inherited-gene-changes-and-mutations-the-genetic-factors-of-lung-cancer\/"],"publisher":[{"@id":"https:\/\/www.regionalcancercare.org\/"}],"author":[{"@type":"Organization","@id":"https:\/\/www.regionalcancercare.org\/news\/inherited-gene-changes-and-mutations-the-genetic-factors-of-lung-cancer\/#BlogPosting_author_Organization","name":"Regional Cancer Care Associates"}],"inLanguage":"en-US","image":[{"@type":"ImageObject","@id":"https:\/\/www.regionalcancercare.org\/news\/inherited-gene-changes-and-mutations-the-genetic-factors-of-lung-cancer\/#BlogPosting_image_ImageObject","url":"https:\/\/www.regionalcancercare.org\/wp-content\/uploads\/2021\/09\/DNA_Strands.jpg"}],"headline":"How Inherited Genetic Mutations Cause Lung Cancer","dateModified":"2021-11-11T14:36:29+00:00","datePublished":"2018-11-29T09:35:47+00:00","description":"Some diseases are genetic, and lung cancer may be one of them. The RCCA blog describes how certain genetic mutations can cause someone to develop lung cancer.","articleBody":"\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\tNovember 29, 2018\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t\t\nMost people associate lung cancer with smoking. While tobacco is the leading cause of lung cancer, it\u2019s not the only one. More and more research is coming out to suggest that some cases can be attributed to inherited genetic mutations. As we learn more about this, doctors at Regional Cancer Care Associates and around the country can help better care for patients with lung cancer.\nThe Relationship between Genes and Cancer\nGenes play a major role in cancer development. They tell cells when to grow and divide. They also tell them when to stop. When genes aren\u2019t doing their job right, some cells may grow and divide uncontrollably. And that\u2019s how cancer starts.\nMost genes become compromised due to outside factors, like tobacco smoke and carcinogenic chemicals. But some genes, researchers believe, are predisposed to changes. That is, when some people are born, their genes are simply more susceptible to lung cancer.\nInherited Genetic Mutations\nWhen lung cancer runs in the family, it could be because of inherited genetic mutations. According to the American Cancer Society, here\u2019s how inherited genetic mutations can affect lung cancer, regardless of whether a person smokes:\nThey can make a person more likely to develop lung cancer.They can reduce a person\u2019s ability to eliminate cancer-causing chemicals from the body.They cause faulty DNA repair mechanisms.\nBut just because you have the mutations, it doesn\u2019t mean you\u2019re going to get lung cancer. It does mean, however, that you are at an increased risk. These inherited mutations have been linked to several different types of lung cancer, including non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC).\nTargeted Treatment Options\nToday, genetic testing allows doctors to learn more about someone\u2019s cancer. There are even new treatment options available that target specific gene changes. For example, drugs like dabrafenib (Tafinlar) and trametinib (Mekinist) can target lung cancer cells that have changes in the BRAF gene. This offers new hope to patients with lung cancer.\nIf you or someone you know has been diagnosed with lung cancer, come to Regional Cancer Care Associates. We develop a personalized treatment plan for every case of lung cancer.\nwe are here for you\nFor more information or to schedule an appointment, call (844) 480-0156. You can also schedule an appointment by calling the RCCA location nearest you.\nRELATED ARTICLES\nRegional Cancer Care Associates is one of fewer than 200 medical practices in the country selected to participate in the Oncology Care Model (OCM); a recent Medicare initiative aimed at improving care coordination and access to and quality of care for Medicare beneficiaries undergoing chemotherapy treatment.\n\u00a9 2022 Regional Cancer Care Associates. All rights reserved.","mainEntityOfPage":"https:\/\/www.regionalcancercare.org\/news\/inherited-gene-changes-and-mutations-the-genetic-factors-of-lung-cancer\/"},{"@context":"http:\/\/schema.org","@type":"LocalBusiness","address":{"@type":"PostalAddress","streetAddress":"Corporate Office 25 Main Street, Suite 601","postalCode":"07601","addressRegion":"NJ","addressLocality":"Hackensack","addressCountry":"USA","name":"Postal Address","@id":"https:\/\/www.regionalcancercare.org\/#PostalAddress"},"logo":{"@type":"ImageObject","width":"1024","height":"468","url":"https:\/\/www.regionalcancercare.org\/wp-content\/themes\/rccah\/dist\/images\/RCCA_logo.jpg","@id":"https:\/\/www.regionalcancercare.org\/wp-content\/themes\/rccah\/dist\/images\/RCCA_logo.jpg"},"image":{"@id":"https:\/\/www.regionalcancercare.org\/wp-content\/themes\/rccah\/dist\/images\/RCCA_logo.jpg"},"contactPoint":[{"@type":"ContactPoint","contactOption":"https:\/\/www.regionalcancercare.org\/contact\/#ContactPointOption","availableLanguage":"https:\/\/en.wikipedia.org\/wiki\/English_language","areaServed":["https:\/\/en.wikipedia.org\/wiki\/New_Jersey","https:\/\/en.wikipedia.org\/wiki\/Hackensack,_New_Jersey"],"contactType":"customer support","telephone":"+1 (844) 346-7222","email":"info@regionalcancercare.org","description":"Corporate Office Regional Cancer Care Associates 25 Main Street, Suite 601 Hackensack, NJ 07601 info@regionalcancercare.org Phone: (844) 346-7222","name":"Contact Corporate Office","image":"https:\/\/www.regionalcancercare.org\/wp-content\/uploads\/2017\/06\/RCCA_logo-300x137.jpg","url":"https:\/\/www.regionalcancercare.org\/contact\/","@id":"https:\/\/www.regionalcancercare.org\/contact\/#CorporateOffice"},{"@type":"ContactPoint","contactOption":"https:\/\/www.regionalcancercare.org\/contact\/#ContactPointOption","availableLanguage":"https:\/\/en.wikipedia.org\/wiki\/English_language","areaServed":["https:\/\/en.wikipedia.org\/wiki\/New_Jersey","https:\/\/en.wikipedia.org\/wiki\/Hackensack,_New_Jersey"],"contactType":"customer support","telephone":"+1 (201) 510-0922","email":"msalvemini@regionalcancercare.org","description":"Media Inquiries: Mary Lou Salvemini Regional Cancer Care Associates Phone: (201) 510-0922 Email: msalvemini@regionalcancercare.org","name":"Contact Media Inquiries","image":"https:\/\/www.regionalcancercare.org\/wp-content\/uploads\/2017\/06\/RCCA_logo-300x137.jpg","url":"https:\/\/www.regionalcancercare.org\/contact\/","@id":"https:\/\/www.regionalcancercare.org\/contact\/#MediaInquiries"}],"areaServed":["https:\/\/en.wikipedia.org\/wiki\/Hackensack,_New_Jersey","https:\/\/en.wikipedia.org\/wiki\/New_Jersey"],"additionalType":"https:\/\/en.wikipedia.org\/wiki\/Treatment_of_cancer","alternateName":"RCCA","description":"Leaders in Advanced Compassionate Cancer Care. Fight cancer with leading-edge treatments, experienced skill and local caring\/convenience from one of the nation's largest networks of cancer specialists.","email":"info@regionalcancercare.org","mainEntityOfPage":"https:\/\/www.regionalcancercare.org\/","url":"https:\/\/www.regionalcancercare.org\/","sameAs":["https:\/\/twitter.com\/rgnlcancercare","https:\/\/www.facebook.com\/regionalcancercareassoc","https:\/\/www.linkedin.com\/company\/10059183","https:\/\/www.youtube.com\/channel\/UCFlVzU4UvZcyXBCe9ZSvAUQ"],"telephone":"+1 (844) 346-7222","name":"Regional Cancer Care Associates","@id":"https:\/\/www.regionalcancercare.org\/"}],{"@context":"https:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"News","item":"https:\/\/www.regionalcancercare.org\/news\/#breadcrumbitem"},{"@type":"ListItem","position":2,"name":"How Inherited Genetic Mutations Cause Lung Cancer","item":"https:\/\/www.regionalcancercare.org\/news\/inherited-gene-changes-and-mutations-the-genetic-factors-of-lung-cancer\/#breadcrumbitem"}]}]